hrp0092p1-116 | Pituitary, Neuroendocrinology and Puberty | ESPE2019

How to Approach Systemic Hypersensitivity reactions to Gonadotropin Releasing Hormone Analogues during treatment of Central Precocious Puberty

Kirkgoz Tarik , Karakoc Elif Aydiner , kiykim ayca , Bugrul Fuat , helvacioglu didem , eltan sevgi bilgic , kasap nurhan , ozen ahmet , baris safa , guran Tulay , bereket abdullah , turan serap

Background: Hypersensitivity reactions to gonadotropin releasing hormone analogues (GnRHa) is a rare but serious side effect . Besides, local reactions, urticaria, anaphylaxis, serum disease, Henoch Schonlein Purpura (HSP) have been reported during GnRHa treatment.. Clinicians should be aware of the potential association of GnRHa with systemic hypersensitivity reactions.Case reports: Here, we report nine girls with syste...